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Triptolide inhibits human breast cancer MCF-7 cell growth via downregulation of the ERα-mediated signaling pathway

AIM: To investigate the anticancer mechanisms of triptolide, a diterpenoid isolated from the plant Tripterygium wilfordii Hook F, against human breast cancer cells and the involvement of the estrogen receptor-α (ERα)-mediated signaling pathway in particular. METHODS: Human breast cancer ERα-positive...

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Dettagli Bibliografici
Pubblicato in:Acta Pharmacol Sin
Autori principali: Li, Han, Pan, Guo-feng, Jiang, Zhen-zhou, Yang, Jing, Sun, Li-xin, Zhang, Lu-yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422943/
https://ncbi.nlm.nih.gov/pubmed/25864647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.162
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