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Imaging MS in Toxicology: An Investigation of Juvenile Rat Nephrotoxicity Associated with Dabrafenib Administration

As part of an investigative nephrotoxicity study, kidney tissues from juvenile rats orally administered dabrafenib at different age intervals between postnatal day (PND) 7 to 35 were investigated by MALDI and LDI imaging mass spectrometry (IMS) to determine the chemical composition of tubular deposi...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Groseclose, M. Reid, Laffan, Susan B., Frazier, Kendall S., Hughes-Earle, Angela, Castellino, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422858/
https://ncbi.nlm.nih.gov/pubmed/25804893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-015-1103-4
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