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Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.

Grb2 is a 25-kDa adaptor protein composed of a Src homology 2 (SH2) domain and two flanking Src homology 3 (SH3) domains. One function of Grb2 is to couple tyrosine-phosphorylated proteins (through its SH2 domain) to downstream effectors (through its SH3 domains). Using an overlay assay, we have ide...

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Autores principales: McPherson, P S, Czernik, A J, Chilcote, T J, Onofri, F, Benfenati, F, Greengard, P, Schlessinger, J, De Camilli, P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC44227/
https://ncbi.nlm.nih.gov/pubmed/8022809
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