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Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets

The close immunological and physiological resemblance with humans makes non-human primates a valuable model for studying influenza virus pathogenesis and immunity and vaccine efficacy against infection. Although both cynomolgus and rhesus macaques are frequently used in influenza virus research, a d...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mooij, Petra, Koopman, Gerrit, Mortier, Daniëlla, van Heteren, Melanie, Oostermeijer, Herman, Fagrouch, Zahra, de Laat, Rudy, Kobinger, Gary, Li, Yan, Remarque, Edmond J., Kondova, Ivanela, Verschoor, Ernst J., Bogers, Willy M. J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422689/
https://ncbi.nlm.nih.gov/pubmed/25946071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126132
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