Mutations in RECQL Gene Are Associated with Predisposition to Breast Cancer

The genetic cause for approximately 80% of familial breast cancer patients is unknown. Here, by sequencing the entire exomes of nine early-onset familial breast cancer patients without BRCA1/2 mutations (diagnosed with breast cancer at or before the age of 35) we found that two index cases carried a...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Sun, Jie, Wang, Yuxia, Xia, Yisui, Xu, Ye, Ouyang, Tao, Li, Jinfeng, Wang, Tianfeng, Fan, Zhaoqing, Fan, Tie, Lin, Benyao, Lou, Huiqiang, Xie, Yuntao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422667/
https://ncbi.nlm.nih.gov/pubmed/25945795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005228
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