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Inhibition of the activation of Hageman factor (factor XII) by complement subcomponent C1q.

Hageman factor (HF, Factor XII) is activated by glass, collagen, and ellagic acid, and initiates blood coagulation via the intrinsic pathway. C1q inhibits collagen-induced platelet aggregation and adherence of platelets to glass, effects attributable to the collagen-like region of C1q. We examined t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Rehmus, E H, Greene, B M, Everson, B A, Ratnoff, O D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3038961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113100
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