BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma

BACKGROUND: Malignant mesothelioma (MM) arises from mesothelial cells that line the pleural, peritoneal and pericardial surfaces. The majority of MMs are pleural and have been associated with asbestos exposure. Previously, pleural MMs have been genetically characterized by the loss of BAP1 (40-60%)...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Alakus, Hakan, Yost, Shawn E, Woo, Brian, French, Randall, Lin, Grace Y, Jepsen, Kristen, Frazer, Kelly A, Lowy, Andrew M, Harismendy, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422481/
https://ncbi.nlm.nih.gov/pubmed/25889843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0485-1
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