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Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes.

Regulatory sequences of the human fetal gamma-globin gene were studied by constructing composite gamma/beta globin promoters and comparing their function to that of intact beta promoters in human K562 cells. The beta-globin gene with either 1,600 or 127 basepairs of beta promoter sequence was not ex...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Lin, H J, Anagnou, N P, Rutherford, T R, Shimada, T, Nienhuis, A W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442247/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3611352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113082
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