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Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate.

We have investigated the inhibitory potential of prostaglandin E2 (PGE2) with respect to intracellular messengers implicated in the signaling system of T-lymphocyte activation pathway. Using the fluorescent indicator Quin 2, it is demonstrated that PGE2 inhibits the increase in cytosolic-free calciu...

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Main Authors: Chouaib, S, Robb, R J, Welte, K, Dupont, B
格式: Artigo
語言:Inglês
出版: 1987
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC442242/
https://ncbi.nlm.nih.gov/pubmed/3038954
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