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Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications

The nitric oxide (NO) and cyclooxygenase (COX) pathways share a number of similarities. Nitric oxide is the mediator generated from the NO synthase (NOS) pathway, and COX converts arachidonic acid to prostaglandins, prostacyclin, and thromboxane A(2). Two major forms of NOS and COX have been identif...

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Bibliographic Details
Published in:Am J Physiol Regul Integr Comp Physiol
Main Authors: Salvemini, Daniela, Kim, Sangwon F., Mollace, Vincenzo
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422342/
https://ncbi.nlm.nih.gov/pubmed/23389111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00355.2012
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