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Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine

INTRODUCTION: Tissue reperfusion following hemorrhagic shock may paradoxically cause tissue injury and organ dysfunction by mitochondrial free radical expression. Both nitrite and carbon monoxide (CO) may protect from this reperfusion injury by limiting mitochondrial free radial production. We explo...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Haugaa, Håkon, Gómez, Hernando, Maberry, Donald R, Holder, Andre, Ogundele, Olufunmilayo, Quintero, Ana Maria B, Escobar, Daniel, Tønnessen, Tor Inge, Airgood, Hannah, Dezfulian, Cameron, Kenny, Elizabeth, Shiva, Sruti, Zuckerbraun, Brian, Pinsky, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422303/
https://ncbi.nlm.nih.gov/pubmed/25899004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0903-z
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