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Killing of human melanoma cells by the membrane attack complex of human complement as a function of its molecular composition.
The efficiency of the membrane attack complex (MAC) in killing M21 melanoma cells was determined varying the molar ratio of cell-bound C9:C8. It was found that C5b-8 produced functional channels as evidenced by 86Rb release and propidium iodide uptake; cell killing occurred in the absence of C9 with...
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| Publicado en: | J Clin Invest |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1987
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3597774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113052 |
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