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Stimulation of insulin secretion reveals heterogeneity of pancreatic B cells in vivo.

We examined the immunofluorescence and ultrastructural changes of insulin-producing B cells in the center and at the periphery of islets of Langerhans during in vivo stimulation by glucose and glibenclamide. A decreased insulin immunostaining was detected in islets from the splenic rat pancreas afte...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Stefan, Y, Meda, P, Neufeld, M, Orci, L
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442216/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110211/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113045
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