Balanced splicing at the Tat-specific HIV-1 3′ss A3 is critical for HIV-1 replication

BACKGROUND: The viral regulatory protein Tat is essential for establishing a productive transcription from the 5′-LTR promoter during the early phase of viral gene expression. Formation of the Tat-encoding mRNAs requires splicing at the viral 3′ss A3, which has previously been shown to be both negat...

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Détails bibliographiques
Publié dans:Retrovirology
Auteurs principaux: Erkelenz, Steffen, Hillebrand, Frank, Widera, Marek, Theiss, Stephan, Fayyaz, Anaam, Degrandi, Daniel, Pfeffer, Klaus, Schaal, Heiner
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422144/
https://ncbi.nlm.nih.gov/pubmed/25889056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0154-8
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