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Arthrogryposis–renal dysfunction–cholestasis (ARC) syndrome: from molecular genetics to clinical features

ABSTRACT: Arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome is a rare but fatal autosomal recessive multisystem disorder caused by mutations in the VPS33B or VIPAR gene. The classical presentation of ARC includes congenital joint contractures, renal tubular dysfunction, and cholestasis. Ad...

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Detalhes bibliográficos
Publicado no:Ital J Pediatr
Main Authors: Zhou, Yaoyao, Zhang, Junfeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422138/
https://ncbi.nlm.nih.gov/pubmed/25239142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13052-014-0077-3
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