Nalaganje...
Deficiency of the reduced nicotinamide adenine dinucleotide dehydrogenase component of complex I of mitochondrial electron transport. Fatal infantile lactic acidosis and hypermetabolism with skeletal-cardiac myopathy and encephalopathy.
A mitochondrial defect was investigated in an infant with fatal congenital lactic acidosis (3-14 mM), high lactate-to-pyruvate ratio, hypotonia, and cardiomyopathy. His sister had died with a similar disorder. Resting oxygen consumption was 150% of controls. Pathological findings included increased...
Shranjeno v:
| izdano v: | J Clin Invest |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
1987
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113066 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|