Wilms’ tumor gene 1 regulates p63 and promotes cell proliferation in squamous cell carcinoma of the head and neck

BACKGROUND: Wilms’ tumor gene 1 (WT1) can act as a suppressor or activator of tumourigenesis in different types of human malignancies. The role of WT1 in squamous cell carcinoma of the head and neck (SCCHN) is not clear. Overexpression of WT1 has been reported in SCCHN, suggesting a possible oncogen...

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Vydáno v:BMC Cancer
Hlavní autoři: Li, Xingru, Ottosson, Sofia, Wang, Sihan, Jernberg, Emma, Boldrup, Linda, Gu, Xiaolian, Nylander, Karin, Li, Aihong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421988/
https://ncbi.nlm.nih.gov/pubmed/25929687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1356-0
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