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Transgenic Mice Enriched in Omega-3 Fatty Acids Are More Susceptible to Pulmonary Tuberculosis: Impaired Resistance to Tuberculosis in fat-1 Mice

BACKGROUND: Besides their health benefits, dietary omega-3 fatty acids (n-3 PUFAs) can impair host resistance to intracellular pathogens. Previously, we and others have showed that n-3 PUFA–treated macrophages poorly control Mycobacterium tuberculosis infection in vitro. METHODS: Wild-type and fat-1...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Bonilla, Diana L., Fan, Yang-Yi, Chapkin, Robert S., McMurray, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421876/
https://ncbi.nlm.nih.gov/pubmed/20053136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/650344
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