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Lipid exposure elicits differential responses in gene expression and DNA methylation in primary human skeletal muscle cells from severely obese women

The skeletal muscle of obese individuals exhibits an impaired ability to increase the expression of genes linked with fatty acid oxidation (FAO) upon lipid exposure. The present study determined if this response could be attributed to differential DNA methylation signatures. RNA and DNA were isolate...

詳細記述

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書誌詳細
出版年:Physiol Genomics
主要な著者: Maples, Jill M., Brault, Jeffrey J., Shewchuk, Brian M., Witczak, Carol A., Zou, Kai, Rowland, Naomi, Hubal, Monica J., Weber, Todd M., Houmard, Joseph A.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421792/
https://ncbi.nlm.nih.gov/pubmed/25670728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00065.2014
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