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Lipid exposure elicits differential responses in gene expression and DNA methylation in primary human skeletal muscle cells from severely obese women

The skeletal muscle of obese individuals exhibits an impaired ability to increase the expression of genes linked with fatty acid oxidation (FAO) upon lipid exposure. The present study determined if this response could be attributed to differential DNA methylation signatures. RNA and DNA were isolate...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Physiol Genomics
मुख्य लेखकों: Maples, Jill M., Brault, Jeffrey J., Shewchuk, Brian M., Witczak, Carol A., Zou, Kai, Rowland, Naomi, Hubal, Monica J., Weber, Todd M., Houmard, Joseph A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421792/
https://ncbi.nlm.nih.gov/pubmed/25670728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00065.2014
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