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E2F1-Mediated FOS Induction in Arsenic Trioxide–Induced Cellular Transformation: Effects of Global H3K9 Hypoacetylation and Promoter-Specific Hyperacetylation in Vitro

Background: Aberrant histone acetylation has been observed in carcinogenesis and cellular transformation associated with arsenic exposure; however, the molecular mechanisms and cellular outcomes of such changes are poorly understood. Objective: We investigated the impact of tolerated and toxic arsen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Environ Health Perspect
Päätekijät: Rahman, Sunniyat, Housein, Zjwan, Dabrowska, Aleksandra, Mayán, Maria Dolores, Boobis, Alan R., Hajji, Nabil
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: NLM-Export 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421767/
https://ncbi.nlm.nih.gov/pubmed/25574600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408302
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