Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution.

We describe here the 1.7-A resolution structure of a single-chain antibody variable domain (scFv) molecule, based on the carbohydrate-binding antibody Se155-4, complexed with the trisaccharide ligand alpha-D-Gal(1-->2)[alpha-D-Abe(1-->3)]alpha-D-Manp1-->OMe, where Abe is abequose. The scFv...

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Bibliografiske detaljer
Main Authors: Zdanov, A, Li, Y, Bundle, D R, Deng, S J, MacKenzie, C R, Narang, S A, Young, N M, Cygler, M
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC44214/
https://ncbi.nlm.nih.gov/pubmed/7517550
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