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Metabolomics Profiling to Investigate the Pharmacologic Mechanisms of Berberine for the Treatment of High-Fat Diet-Induced Nonalcoholic Steatohepatitis

Objective. Berberine has been used to treat nonalcoholic steatohepatitis (NASH), which has been addressed in many studies. In this study, we investigated the molecular pharmacology mechanisms of berberine using metabolomic techniques. Methods. Sprague-Dawley rats were randomly divided into three gro...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Li, Jian, Liu, Zezhou, Guo, Mingxing, Xu, Kejia, Jiang, Miao, Lu, Aiping, Gao, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421035/
https://ncbi.nlm.nih.gov/pubmed/25977701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/897914
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