Peripheral insulin resistance in obese girls with hyperandrogenism is related to oxidative phosphorylation and elevated serum free fatty acids

Hyperandrogenic syndrome (HAS) is associated with insulin resistance (IR) and type 2 diabetes. Muscle IR in type 2 diabetes is linked with defects in mitochondrial oxidative capacity. In vivo muscle mitochondrial function has not been studied in HAS, especially in youth, who are early in the disease...

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Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: Cree-Green, Melanie, Newcomer, Bradley R., Coe, Gregory, Newnes, Lindsey, Baumgartner, Amy, Brown, Mark S., Pyle, Laura, Reusch, Jane E., Nadeau, Kristen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420897/
https://ncbi.nlm.nih.gov/pubmed/25714677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00619.2014
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