TAK-242, an antagonist for Toll-like receptor 4, protects against acute cerebral ischemia/reperfusion injury in mice

Toll-like receptor 4 (TLR4) contributes to cerebral ischemia/reperfusion (I/R) injury and is a potential target for the treatment of ischemic stroke. This experiment is to evaluate the effect of an exogenous TLR4 antagonist, TAK-242, against acute cerebral I/R injury. A mouse model of cerebral I/R w...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Hua, Fang, Tang, Huiling, Wang, Jun, Prunty, Megan C, Hua, Xiaodong, Sayeed, Iqbal, Stein, Donald G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420883/
https://ncbi.nlm.nih.gov/pubmed/25586141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.240
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