Increased CD1c(+) mDC1 with mature phenotype regulated by TNFα-p38 MAPK in autoimmune ocular inflammatory disease

In this study we investigated the role of blood CD1c(+) myeloid dendritic cells 1 (mDC1), a key mDC subtype, in patients with autoimmune uveitis. We observed a significant increase of blood CD1c(+) mDC1 in uveitis patients. The increased CD1c(+) mDC1 exhibited high HLADR expression and less antigen...

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Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Chen, Ping, Denniston, Alastair, Hannes, Susan, Tucker, William, Wei, Lai, Liu, Baoying, Xiao, Tiaojiang, Hirani, Sima, Li, Zhiyu, Jawad, Shayma, Si, Han, Lee, Richard W.J., Sen, H. Nida, Nussenblatt, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420697/
https://ncbi.nlm.nih.gov/pubmed/25784146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.03.002
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