Sulindac has strong antifibrotic effects by suppressing STAT3-related miR-21

Pulmonary fibrosis (PF) is a disease with an unknown cause and a poor prognosis. In this study, we aimed to explore the pathogenesis of PF and the mechanism of sulindac in attenuating bleomycin (BLM)-induced PF. The rat PF model was induced by BLM and verified through histological studies and hydrox...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhou, Xue, Li, You-Jie, Gao, Shu-Yan, Wang, Xiao-Zhi, Wang, Ping-Yu, Yan, Yun-Fei, Xie, Shu-Yang, Lv, Chang-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420612/
https://ncbi.nlm.nih.gov/pubmed/25704671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12506
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