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Inherent dynamics within the Crimean-Congo Hemorrhagic fever virus protease are localized to the same region as substrate interactions

Crimean-Congo Hemorrhagic fever virus (CCHFV) is one of several lethal viruses that encodes for a viral ovarian tumor domain (vOTU), which serves to cleave and remove ubiquitin (Ub) and interferon stimulated gene product 15 (ISG15) from numerous proteins involved in cellular signaling. Such manipula...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Eisenmesser, Elan Z, Capodagli, Glenn C, Armstrong, Geoffrey S, Holliday, Michael J, Isern, Nancy G, Zhang, Fengli, Pegan, Scott D
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420516/
https://ncbi.nlm.nih.gov/pubmed/25564798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2637
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