Immobilization of Zidovudine Derivatives on the SBA-15 Mesoporous Silica and Evaluation of Their Cytotoxic Activity

Novel zidovudine derivatives, able to be covalently conjugated to silica surface, have been obtained and grafted to SBA-15 mesoporous silica. Cytotoxic activity of the hybrid organic-inorganic (zidovudine derivatives-silica) systems against HeLa and KB cell lines has been analyzed. Addition of folic...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Lewandowski, Dawid, Lewandowska, Marta, Ruszkowski, Piotr, Pińska, Anita, Schroeder, Grzegorz
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420263/
https://ncbi.nlm.nih.gov/pubmed/25942021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126251
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