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Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance

Antimicrobial chemotherapy is critical in the fight against infectious diseases caused by Entamoeba histolytica. Among the drugs available for the treatment of amebiasis, metronidazole (MTZ) is considered the drug of choice. Recently, in vitro studies have described MTZ resistance and the potential...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Penuliar, Gil M., Nakada-Tsukui, Kumiko, Nozaki, Tomoyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419850/
https://ncbi.nlm.nih.gov/pubmed/25999919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00354
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