IGF-I Influences Everolimus Activity in Medullary Thyroid Carcinoma

CONTEXT: Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. It has been previously demonstrated that insulin-like growth factor I (IGF-I) protects MTC from the effects of antiproliferative drugs. Everolimus, an mTOR inhibitor, has shown potent antiprol...

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Bibliografski detalji
Izdano u:Front Endocrinol (Lausanne)
Glavni autori: Gentilin, Erica, Di Pasquale, Carmelina, Rossi, Martina, Tagliati, Federico, Gagliano, Teresa, Rossi, Roberta, Pelizzo, Mariarosa, Merante Boschin, Isabella, degli Uberti, Ettore C., Zatelli, Maria Chiara
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Endocrinology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419838/
https://ncbi.nlm.nih.gov/pubmed/25999915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2015.00063
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