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IGF-I Influences Everolimus Activity in Medullary Thyroid Carcinoma
CONTEXT: Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. It has been previously demonstrated that insulin-like growth factor I (IGF-I) protects MTC from the effects of antiproliferative drugs. Everolimus, an mTOR inhibitor, has shown potent antiprol...
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| Pubblicato in: | Front Endocrinol (Lausanne) |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419838/ https://ncbi.nlm.nih.gov/pubmed/25999915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2015.00063 |
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