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Modulation of Insulin-Like Growth Factor-1 Receptor and its Signaling Network for the Treatment of Cancer: Current Status and Future Perspectives

Based on over three decades of pre-clinical data, insulin-like growth factor-1 receptor (IGF-1R) signaling has gained recognition as a promoter of tumorogenesis, driving cell survival and proliferation in multiple human cancers. As a result, IGF-1R has been pursued as a target for cancer treatment....

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Detalhes bibliográficos
Publicado no:Oncol Rev
Main Authors: Jin, Meizhong, Buck, Elizabeth, Mulvihill, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: PAGEPress Publications, Pavia, Italy 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419619/
https://ncbi.nlm.nih.gov/pubmed/25992224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/oncol.2013.e3
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