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3D Structural Fluctuation of IgG1 Antibody Revealed by Individual Particle Electron Tomography

Commonly used methods for determining protein structure, including X-ray crystallography and single-particle reconstruction, often provide a single and unique three-dimensional (3D) structure. However, in these methods, the protein dynamics and flexibility/fluctuation remain mostly unknown. Here, we...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Zhang, Xing, Zhang, Lei, Tong, Huimin, Peng, Bo, Rames, Matthew J., Zhang, Shengli, Ren, Gang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419541/
https://ncbi.nlm.nih.gov/pubmed/25940394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09803
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