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3-Glucosylated 5-amino-1,2,4-oxadiazoles: synthesis and evaluation as glycogen phosphorylase inhibitors

Glycogen phosporylase (GP) is a promising target for the control of glycaemia. The design of inhibitors binding at the catalytic site has been accomplished through various families of glucose-based derivatives such as oxadiazoles. Further elaboration of the oxadiazole aromatic aglycon moiety is now...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Donnier-Maréchal, Marion, Goyard, David, Folliard, Vincent, Docsa, Tibor, Gergely, Pal, Praly, Jean-Pierre, Vidal, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419504/
https://ncbi.nlm.nih.gov/pubmed/25977724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.56
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