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Identification of core active disaccharides in heparin for HGF-inducing activity

OBJECTIVES: To ascertain the positions of sulfated groups for HGF-inducing activity using differently sulfated heparin disaccharides and to investigate whether the heparin disaccharide elevates HGF levels in plasma in vivo and exerts protective effects on acute liver injury. MATERIALS AND METHODS: T...

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Publicado en:J Pharmacol Pharmacother
Autores principales: Kato, Takashi, Sakiyama, Ryoichi, Oka, Kiyomasa, Nakamura, Toshikazu
Formato: Artigo
Lenguaje:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419252/
https://ncbi.nlm.nih.gov/pubmed/25969653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-500X.155483
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