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Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer

Breast cancer metastasis is the leading cause of cancer-related deaths in women worldwide. Collagen in the tumor microenvironment plays a crucial role in regulating tumor progression. We have shown that type III collagen (Col3), a component of tumor stroma, regulates myofibroblast differentiation an...

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Publicat a:Am J Pathol
Autors principals: Brisson, Becky K., Mauldin, Elizabeth A., Lei, Weiwei, Vogel, Laurie K., Power, Ashley M., Lo, Albert, Dopkin, Derek, Khanna, Chand, Wells, Rebecca G., Puré, Ellen, Volk, Susan W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419211/
https://ncbi.nlm.nih.gov/pubmed/25795282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.01.029
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