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Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion

Several studies indicate that the activity of cruzipain, the main lysosomal cysteine peptidase of Trypanosoma cruzi, contributes to parasite infectivity. In addition, the parasitic invasion process of mammalian host cells is described to be dependent on the activation of the host TGF-β signaling pat...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Ferrão, Patrícia Mello, d'Avila-Levy, Claudia Masini, Araujo-Jorge, Tania Cremonini, Degrave, Wim Maurits, Gonçalves, Antônio da Silva, Garzoni, Luciana Ribeiro, Lima, Ana Paula, Feige, Jean Jacques, Bailly, Sabine, Mendonça-Lima, Leila, Waghabi, Mariana Caldas
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418758/
https://ncbi.nlm.nih.gov/pubmed/25938232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124832
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