Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion

Several studies indicate that the activity of cruzipain, the main lysosomal cysteine peptidase of Trypanosoma cruzi, contributes to parasite infectivity. In addition, the parasitic invasion process of mammalian host cells is described to be dependent on the activation of the host TGF-β signaling pat...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Ferrão, Patrícia Mello, d'Avila-Levy, Claudia Masini, Araujo-Jorge, Tania Cremonini, Degrave, Wim Maurits, Gonçalves, Antônio da Silva, Garzoni, Luciana Ribeiro, Lima, Ana Paula, Feige, Jean Jacques, Bailly, Sabine, Mendonça-Lima, Leila, Waghabi, Mariana Caldas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418758/
https://ncbi.nlm.nih.gov/pubmed/25938232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124832
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