IgG(4) inhibits peanut-induced basophil and mast cell activation in peanut-tolerant children sensitized to peanut major allergens

BACKGROUND: Most children with detectable peanut-specific IgE (P-sIgE) are not allergic to peanut. We addressed 2 non–mutually exclusive hypotheses for the discrepancy between allergy and sensitization: (1) differences in P-sIgE levels between children with peanut allergy (PA) and peanut-sensitized...

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Veröffentlicht in:J Allergy Clin Immunol
Hauptverfasser: Santos, Alexandra F., James, Louisa K., Bahnson, Henry T., Shamji, Mohammed H., Couto-Francisco, Natália C., Islam, Sabita, Houghton, Sally, Clark, Andrew T., Stephens, Alick, Turcanu, Victor, Durham, Stephen R., Gould, Hannah J., Lack, Gideon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mosby 2015
Schlagworte:
Food, Drug, Insect Sting Allergy, and Anaphylaxis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418748/
https://ncbi.nlm.nih.gov/pubmed/25670011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.01.012
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