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Predicting Peptide-Mediated Interactions on a Genome-Wide Scale

We describe a method to predict protein-protein interactions (PPIs) formed between structured domains and short peptide motifs. We take an integrative approach based on consensus patterns of known motifs in databases, structures of domain-motif complexes from the PDB and various sources of non-struc...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Chen, T. Scott, Petrey, Donald, Garzon, Jose Ignacio, Honig, Barry
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418708/
https://ncbi.nlm.nih.gov/pubmed/25938916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004248
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