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Variants in Nebulin (NEB) Are Linked to the Development of Familial Primary Angle Closure Glaucoma in Basset Hounds

Several dog breeds are susceptible to developing primary angle closure glaucoma (PACG), which suggests a genetic basis for the disease. We have identified a four-generation Basset Hound pedigree with characteristic autosomal recessive PACG that closely recapitulates PACG in humans. Our aim is to uti...

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Veröffentlicht in:PLoS One
Hauptverfasser: Ahram, Dina F., Grozdanic, Sinisa D., Kecova, Helga, Henkes, Arjen, Collin, Rob W. J., Kuehn, Markus H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418656/
https://ncbi.nlm.nih.gov/pubmed/25938837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126660
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