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Fully Degradable Hydrophilic Polyals for Protein Modification
Modification of proteins with hydrophilic polymers is an effective strategy for regulation of protein pharmacokinetics. However, conjugates of slowly or nonbiodegradable materials, such as poly(ethylene glycol), are known to cause long-lasting cell vacuolization, in particular in renal epithelium. C...
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| Publicado no: | Biomacromolecules |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418481/ https://ncbi.nlm.nih.gov/pubmed/16153103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm049210k |
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