The Common Chymotrypsinogen C (CTRC) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population

OBJECTIVES: Recurrent acute pancreatitis (RAP) is a complex inflammatory disorder that may progress to fibrosis and other irreversible features recognized as chronic pancreatitis (CP). Chymotrypsinogen C (CTRC) protects the pancreas by degrading prematurely activated trypsinogen. Rare mutations are...

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Publicado en:Clin Transl Gastroenterol
Autores principales: LaRusch, Jessica, Lozano-Leon, Antonio, Stello, Kimberly, Moore, Amanda, Muddana, Venkata, O'Connell, Michael, Diergaarde, Brenda, Yadav, Dhiraj, Whitcomb, David C
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Contribution
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418406/
https://ncbi.nlm.nih.gov/pubmed/25569187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2014.13
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