Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced β-cell damage and the development of type 1 diabetes

The axis of nuclear factor κB (NF-κB)-inducible NO synthase (iNOS)-nitric oxide plays a key role in cytokine- and streptozotocin-mediated pancreatic β-cell damage. In this study, we investigated the effects of kazinol C and isokazinol D isolated from Broussonetia kazinoki on the β-cell viability and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Mol Med
Prif Awduron: Bae, Ui-Jin, Jang, Hyun-Young, Lim, Jung Min, Hua, Li, Ryu, Jae-Ha, Park, Byung-Hyun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418042/
https://ncbi.nlm.nih.gov/pubmed/25907110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.16
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