Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced β-cell damage and the development of type 1 diabetes

The axis of nuclear factor κB (NF-κB)-inducible NO synthase (iNOS)-nitric oxide plays a key role in cytokine- and streptozotocin-mediated pancreatic β-cell damage. In this study, we investigated the effects of kazinol C and isokazinol D isolated from Broussonetia kazinoki on the β-cell viability and...

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Detalles Bibliográficos
Publicado en:Exp Mol Med
Main Authors: Bae, Ui-Jin, Jang, Hyun-Young, Lim, Jung Min, Hua, Li, Ryu, Jae-Ha, Park, Byung-Hyun
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418042/
https://ncbi.nlm.nih.gov/pubmed/25907110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.16
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