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Evolving concepts of tumor heterogeneity

Past and recent findings on tumor heterogeneity have led clinicians and researchers to broadly define cancer development as an evolving process. This evolutionary model of tumorigenesis has largely been shaped by seminal reports of fitness-promoting mutations conferring a malignant cellular phenotyp...

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Bibliographic Details
Published in:Cell Biosci
Main Authors: Zellmer, Victoria R, Zhang, Siyuan
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417538/
https://ncbi.nlm.nih.gov/pubmed/25937891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-4-69
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