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Diverse binding modes, same goal: the receptor recognition mechanism of botulinum neurotoxin

Botulinum neurotoxins (BoNTs) are among the most deadly toxins known. They act rapidly in a highly specific manner to block neurotransmitter release by cleaving the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) complex at neuromuscular junctions. The extreme toxicity...

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Detalhes bibliográficos
Publicado no:Prog Biophys Mol Biol
Main Authors: Lam, Kwok-Ho, Yao, Guorui, Jin, Rongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417461/
https://ncbi.nlm.nih.gov/pubmed/25701633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2015.02.004
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