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Tissue-specific regulation of p38α-mediated inflammation in ConA-induced acute liver damage
Because p38α plays a critical role in inflammation, it has been an attractive target for the development of anti-inflammation therapeutics. However, p38α inhibitors showed side effects including severe liver toxicity that often prevailed over the benefits in clinical studies, and the mechanism of to...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417423/ https://ncbi.nlm.nih.gov/pubmed/25888643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402954 |
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