Epigenetic clustering of gastric carcinomas based on DNA methylation profiles at the precancerous stage: its correlation with tumor aggressiveness and patient outcome

The aim of this study was to clarify the significance of DNA methylation alterations during gastric carcinogenesis. Single-CpG resolution genome-wide DNA methylation analysis using the Infinium assay was performed on 109 samples of non-cancerous gastric mucosa (N) and 105 samples of tumorous tissue...

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Publié dans:Carcinogenesis
Auteurs principaux: Yamanoi, Kazuhiro, Arai, Eri, Tian, Ying, Takahashi, Yoriko, Miyata, Sayaka, Sasaki, Hiroki, Chiwaki, Fumiko, Ichikawa, Hitoshi, Sakamoto, Hiromi, Kushima, Ryoji, Katai, Hitoshi, Yoshida, Teruhiko, Sakamoto, Michiie, Kanai, Yae
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
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Original Manuscript
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417340/
https://ncbi.nlm.nih.gov/pubmed/25740824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv013
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