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Simulation of alcohol action upon a detailed Purkinje neuron model and a simpler surrogate model that runs >400 times faster

BACKGROUND: An approach to investigate brain function/dysfunction is to simulate neuron circuits on a computer. A problem, however, is that detailed neuron descriptions are computationally expensive and this handicaps the pursuit of realistic network investigations, where many neurons need to be sim...

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Detalles Bibliográficos
Publicado en:BMC Neurosci
Autor principal: Forrest, Michael D
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417229/
https://ncbi.nlm.nih.gov/pubmed/25928094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0162-6
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