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A rapid and sensitive high-throughput screening method to identify compounds targeting protein–nucleic acids interactions
DNA-binding and RNA-binding proteins are usually considered ‘undruggable’ partly due to the lack of an efficient method to identify inhibitors from existing small molecule repositories. Here we report a rapid and sensitive high-throughput screening approach to identify compounds targeting protein–nu...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417145/ https://ncbi.nlm.nih.gov/pubmed/25653160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv069 |
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