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Global variability in gene expression and alternative splicing is modulated by mitochondrial content
Noise in gene expression is a main determinant of phenotypic variability. Increasing experimental evidence suggests that genome-wide cellular constraints largely contribute to the heterogeneity observed in gene products. It is still unclear, however, which global factors affect gene expression noise...
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Pubblicato in: | Genome Res |
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Autori principali: | , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Cold Spring Harbor Laboratory Press
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417112/ https://ncbi.nlm.nih.gov/pubmed/25800673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.178426.114 |
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